Jaguars vs. Texans: Odds and Predictions for Week 6 London Showdown at Wembley

The Jacksonville Jaguars (4-1) enter their second consecutive London game as 2.5-point favorites over the Houston Texans (1-4), with kickoff scheduled for 9:30 a.m. ET on Sunday, October 18, at Wembley Stadium. The Jaguars remain in the UK after a last-second 19-17 victory over the Eagles at Tottenham Stadium, while the Texans travel off their first win of the season, a 26-3 triumph over the Tennessee Titans.

Prediction models and expert desks expect a close contest between the AFC South rivals. SportsLine’s simulation-based model projects an Over on the 42-point total, while Yardbarker’s editorial desk projects a 23-20 Jaguars victory, highlighting Jacksonville’s strong run defense and Houston’s clean passing record by quarterback C.J. Stroud.

Key storylines include the Houston offense’s potential shift with the debut of wide receiver Marvin Harrison Jr., who was traded from Arizona, and the Jaguars’ injury struggles. The Jaguars have the NFL’s stingiest run defense, but will test their offensive line depth without left tackle Anton Harrison, who is leaving the UK for surgery.